Zinc efflux through lysosomal exocytosis prevents zinc-induced toxicity
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چکیده
منابع مشابه
Zn efflux through lysosomal exocytosis prevents Zn-induced toxicity
Zn is an essential micronutrient and an important ionic signal whose excess, as well as scarcity, is detrimental to cells. Free cytoplasmic Zn is controlled by a network of Zn transporters and chelating proteins. Recently, lysosomes became the focus of studies in Zn transport, as they were shown to play a role in Zn-induced toxicity by serving as Zn sinks that absorb Zn from the cytoplasm. Here...
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ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 2014
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.145318